FACS bulk enrichment in combination with the VIPS and Cell Metric delivered significant savings for a CDMO

In early 2018, the Cell Line Development (CLD) department at Celonic AG, a European-based CDMO specializing in biologics manufacturing from mammalian cell lines, decided to optimize their workflow by acquiring new technology geared towards shortening their time lines and lightening their workload. In addition, they were searching for a gentler fluidics system for single cell isolation as the shear stress from FACS was restricting recovery and outgrowth for certain cell lines. Implementation of the VIPS™ and Cell Metric® has allowed them to shorten their CLD workflow timeline by nearly 50% and to reduce the number of plates they have to handle by up to 25-fold.