How to Manage Formulation of High Concentration Biologics

We see a trend towards increasingly concentrated drug formulations due, for example, to the decreasing popularity of intravenous administration. This trend presents manufacturing challenges. In this presentation, Parviz Shamlou, Vice President of the Jefferson Institute for Bio-Processing discusses the challenges associated with high concentration and high viscosity monoclonal antibody formulations, how biopharma manages these challenges today and how the Jefferson Institute addresses these issues.

Kendal Studd, Scientific Applications Specialist at Advanced Instruments will close the session by discussing the challenges for analytical devices in testing these formulations and how advances in osmolality testing in particular are applied to help minimize the risks.

Presented by:

• Parviz Ayazi-Shamlou, Vice President & Executive Director – Jefferson Institute for Bioprocessing (JIB)
  Parviz Shamlou is the Vice President & Executive Director at Jefferson Institute for Bioprocessing (JIB) at Thomas Jefferson University (TJU). JIB is a multi-million dollar state-of-the art facility that provides cutting edge training, and research in bioprocessing. Parviz Shamlou has over 30 years a of academic and industry experience in bioprocessing, from ideation to commercial products including protein and monoclonal antibodies, cell and gene therapy and advanced vaccines.

• Kendal Studd, Scientific Applications Specialist – Advanced Instruments
  Kendal specializes in advancing novel osmolality applications within the biopharma industry. She is an experienced scientist with a demonstrated history of working in the biotechnology industry alongside sterilizing grade filters and pharmaceuticals. She graduated from the University of Portsmouth with Distinction in a research Master’s degree looking at DNA extraction and amplification via PCR.