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Clinical Overview Emergency Medicine Internal Medicine/Endocrinology

Surgery/Critical Care

Hypovolemic/Hypervolemic Shock Prevention: Osmolality can be used to monitor perfusate during coronary bypass or renal surgery to avoid hypovolemic shock.

Electrolyte/Metabolyte Imbalance: Osmolality offers rapid detection of post-surgery electrolyte/metabolite imbalance. In urologic surgery, the difference between calculated and measured osmolality can be used to estimate absorption of irrigation fluid.

IV Therapy: Osmolality can help monitor and manage IV therapy.

Liver Transplant: Large increases in osmolality can occur due to blood
loss or transfusion, changes in plasma sodium levels, or the administration of sodium bicarbonate.

Glycine Uptake: Surgical procedures of long duration can cause the uptake of irrigation fluid that will contribute to an elevated osmolality.